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What’s The Difference Between IVF and ICSI? - The main difference between IVF (In Vitro Fertilization) and ICSI (Intracytoplasmic Sperm Injection) lies in the fertilization process. In IVF, eggs and sperm are mixed in a lab dish, and fertilization occurs naturally. In contrast, ICSI involves injecting a single sperm directly into an egg to facilitate fertilization. ICSI is typically recommended for cases of male infertility or previous IVF failure. Pride IVF specializes in both IVF and ICSI procedures, tailoring treatments to individual needs for successful conception.